OVC and OVW FY 2026 Victim Services for Angel Families Program – Invited Notice of Funding Opportunity
This is a notice of funding opportunity (NOFO) for the OVC and OVW FY 2026 Victim Services for Angel Families Program – Invited Notice of Funding Opportunity. This opportunity will fund direct services to crime victims to address their needs and connect them to other resources. Services and referrals provided to victims and surviving Angel families through this program may include, but are not limited to, emergency assistance; case management; shelter and housing; medical and dental care; victim advocacy; transportation; childcare; legal services; employment assistance; and, for victims of domestic/dating violence, sexual assault, and/or stalking, cash assistance to offset the costs of victimization. All services proposed under this program must directly address the needs of crime victims.
O-OVC-2026-172807
Award Ceiling
$500K
Closes
Nov 16, 2026
20d left
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
<p>The purpose of this Notice of Funding Opportunity (NOFO) is to invite Small Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Direct involvement of key stakeholders where appropriate is encouraged. These applications should be for small research projects, such as those that involve single investigators. Of particular interest are projects that propose normative or conceptual analyses, including focused legal, economic, philosophical, anthropological, or historical analyses of new or emerging issues. This mechanism can also be used for the collection of preliminary data and the secondary analysis of existing data.</p>
PAR-25-370
Award Ceiling
$50K
Closes
Nov 16, 2026
20d left
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
<p>The purpose of this NOFO is to invite Exploratory/Developmental Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. Of particular interest are studies that explore the implications of new or emerging genomic technologies or novel uses of genomic information. </p>
PAR-25-369
Award Ceiling
—
Closes
Nov 18, 2026
22d left
Preschool Development Grant Birth Through Five (PDG B-5) SMART Grant
This NOFO is modified. The webinar link was changed and the ECD website address changed. The U.S. Department of Health and Human Services (HHS), Administration for Children and Families (ACF), seeks applications for the Preschool Development Grant Birth through Five (PDG B-5) SMART Grant: Strategic Measurement, Analytics, and Results using Technology. This funding opportunity will support states and territories to make targeted, one-year investments in statewide early care and education (ECE) technology and analytic data infrastructure that advance PDG B-5 purposes, including strengthening coordination across the mixed-delivery system, improving program quality and access, supporting informed family choice, and using data to better understand and address the needs of children from birth through age five. Applicants will propose a focused, feasible investment that strengthens the state's ability to generate actionable information for decision-making and produces a measurable result by the end of the project period.
HHS-2026-ACF-ECD-TP-0039
Award Ceiling
$15.0M
Closes
Nov 20, 2026
24d left
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.
RFA-AT-25-003
Award Ceiling
$375K
Closes
Nov 23, 2026
27d left
OVC FY 2026 Specialized Human Trafficking Assistance: Task Forces and Legal Services
This opportunity will assist OVC-funded multidisciplinary anti-trafficking task forces and teams (MDTs) and legal service providers by offering specialized training to ensure successful outcomes for victims of human trafficking, as defined by 22 U.S.C. § 7102(11). Applicants should propose approaches that strengthen Enhanced Collaborative Model (ECM) task forces, MDTs, and legal service providers’ capacity to identify and serve victims, conduct victim-centered investigations, and successfully prosecute traffickers.
O-OVC-2026-172790
Award Ceiling
$3.0M
Closes
Dec 1, 2026
35d left
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)
The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools.
RFA-OD-24-011
Award Ceiling
—
Closes
Dec 4, 2026
38d left
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
<p>The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).</p>
PAR-25-378
Award Ceiling
—
Closes
Jan 7, 2027
72d left
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).
RFA-NS-25-023
Award Ceiling
$350K
Closes
Jan 15, 2027
80d left
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged.
RFA-MH-26-170
Award Ceiling
—
Closes
Feb 8, 2027
104d left
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.
PA-24-194
Award Ceiling
—
Closes
May 7, 2027
192d left
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)
The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomical or functional changes at any level, including genetics/genomics, single cells, connectomics, neural population activity patterns, and others. This funding opportunity is intended to encourage technological and conceptual innovation to improve repeated measures across longer epochs of the lifespan, to better predict outcomes at later ages.
PAR-25-279
Award Ceiling
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Closes
May 7, 2027
192d left
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.
PA-24-193
Award Ceiling
—
Closes
May 7, 2027
192d left
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs use the K01 to support career development in specific fields.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFO.
PA-24-176
Award Ceiling
—
Closes
May 7, 2027
192d left
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
<p>The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.</p>
PA-24-185
Award Ceiling
—
Closes
May 7, 2027
192d left
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)
The purpose of this notice of funding opportunity (NOFO) is to encourage community-engaged research that broadens the conceptualization of qualities of the environment that can support language development in children and that focuses on the development of novel measures of childrens language development. The overall goal is to build the number of strengths-focused, culturally and linguistically responsive, and generalizable toolsto further our understanding of childrens language development and/or impairment, and predictors thereof.
PAR-25-113
Award Ceiling
—
Closes
Sep 7, 2027
315d left
NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)
The purpose of this Notice of Funding Opportunity (NOFO) is to support the continued operation, maintenance, and dissemination of unique database bioinformatics resources that are of major importance to the research community using animal models of embryonic developmental processes. These grants will support ongoing development and enhancement of the resources, user training and services, provision of community generated data storage and curation, wide dissemination of the tools and/or resources, and expansion of interoperability with other NIH bioinformatics resources.
PAR-24-301
Award Ceiling
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Closes
Sep 25, 2027
333d left
Home Study and Post-Release Services for Unaccompanied Alien Children
This NOFO is modified. Changes are made to Step 1: Review the Opportunity. The Office of Refugee Resettlement (ORR) provides temporary housing and care for children who arrive in the United States alone. These are children who are under 18 years old, don't have legal permission to be in the U.S., and don't have a parent or legal guardian in the U.S. who can take care of them. ORR runs the Home Study and Post-Release Services Program to help these children. Before placing a child with a sponsor, ORR carefully checks potential homes to make sure they're safe and appropriate. After placement, ORR provides ongoing support to help children and their sponsors succeed. This support helps children adjust to living with their sponsor, connect with their community, stay safe and healthy, and navigate the immigration court process. The goal is to make sure children are placed in safe homes and have the support they need to thrive while their immigration cases move forward.
HHS-2026-ACF-ORR-ZU-0019
Award Ceiling
$100.0M
Closes
Oct 1, 2027
339d left
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future.Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. This FOA defines a "high priority" condition as one where screening is not currently recommended, but infants with the condition would significantly benefit from early identification and treatment.
PAR-25-265
Award Ceiling
—
Closes
Nov 16, 2027
385d left
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)
This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future.Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. This FOA defines a "high priority" condition as one where screening is not currently recommended, but infants with the condition would significantly benefit from early identification and treatment.
PAR-25-266
Award Ceiling
$200K
Closes
Nov 16, 2027
385d left