Grants/education

Federal Grants

education Grants

Open federal grant opportunities in education. Deadlines, award amounts, and agency contacts — all sourced from Grants.gov.

63 open grantsPage 1 of 4
Library of CongressClosing soon

Lewis-Houghton Civics and Democracy Initiative: New Awards for 2027-2029

<p>This funding opportunity is authorized under the “Legislative Branch Appropriations Act of 2023” (Pub. L. 117-389 (H.R. 8237)), subject to availability of funding. The resulting awards will be subject to the Library of Congress Regulation (LCR) 7-310. In addition, while the Library, as a legislative agency, is not subject to <a href="https://www.ecfr.gov/current/title-2/subtitle-A/chapter-II/part-200?toc=1" target="_blank">2 CFR 200 – Uniform Administrative Requirements, Costs Principles and Audit Requirements for Federal Awards</a>, the resulting awards will be subject to selective provisions of 2 CFR 200 as determined by the Library and indicated in this NOFO.&nbsp;&nbsp;&nbsp;</p> <p><br></p> <p><strong>About the Library of Congress</strong></p> <p>The Library of Congress is the largest library in the world, with <a href="https://www.loc.gov/about/general-information/#year-at-a-glance" target="_blank">millions of books, films and video, audio recordings, photographs, newspapers, maps and manuscripts</a> in its collections. The Library is the main research arm of the U.S. Congress. It is the nation’s oldest federal cultural institution.</p> <p><br></p> <p>The Library’s mission is to engage, inspire, and inform Congress and the American people with a universal and enduring source of knowledge and creativity.</p> <p><br></p> <p><strong>About the Teaching with Primary Sources Program (TPS)</strong></p> <p>The Teaching with Primary Sources program (<a href="http://www.loc.gov/teachers" target="_blank">www.loc.gov/teachers</a>) has been the Library of Congress’s premier educational grant program since 2006. The goals of the program have included providing instructional materials, tools, education and professional development that enhance teachers’ ability to integrate digitized primary sources from the Library of Congress into instruction that builds student literacy, critical thinking skills, content knowledge and ability to conduct original research. Since the establishment of the Center for Learning, Literacy and Engagement in 2018, and the release of the Library’s 2024-2028 Strategic Plan, the TPS goals both influence and reflect the Library’s broader outreach goals.</p> <p>&nbsp;</p> <p><strong>About the Lewis-Houghton Civics and Democracy Initiative (LHI)</strong></p> <p>Named in honor of Rep. John R. Lewis (D-GA) and Rep. Amo Houghton (R-NY), the Lewis-Houghton Civics and Democracy Initiative (LHI) is included under the Teaching with Primary Sources (TPS) program. In the joint explanatory statement for the Legislative Branch Appropriations Act, 2023, Congress established the Lewis-Houghton Civics and Democracy Initiative and appropriated funds to the Library of Congress to award grants to eligible organizations within the United States (U.S.) and its territories to develop digitally-enabled, creative arts-driven projects focused on using the digitized primary sources of the Library of Congress to teach history, civics and/or democracy. More information and a description of past LHI-funded projects can be found at: <a href="https://www.loc.gov/programs/teachers/about-this-program/teaching-with-primary-sources-partner-program/lewis-houghton/" target="_blank">https://www.loc.gov/programs/teachers/about-this-program/teaching-with-primary-sources-partner-program/lewis-houghton/</a>.</p> <p>&nbsp;</p> <p><strong>TPS Educational Consortium</strong></p> <p>Grantee organizations become members of the TPS Educational Consortium. They include a wide variety of educational organizations including school districts, libraries, cultural institutions, universities and technology firms that have received Library funding to deliver teacher professional development, create teaching materials and develop apps and online interactives, based on Library of Congress materials.</p> <p><br></p> <p>TPS Consortium members are valued as “Connectors” who help the Library achieve its vision of connecting to all Americans. TPS Consortium members extend the Library’s reach by connecting hundreds of thousands of American educators and learners, including K-12 teachers and their students, to Library of Congress methods and materials. Consortium members collaborate, co-create, share ideas, network and actively participate as an educational community.</p> <p><br></p> <p>&nbsp;<strong>Purpose</strong></p> <p>The purpose of this notice is for the Library of Congress to solicit project proposals from eligible organizations and select awardee organizations that will design and implement educational projects in which the Library’s music or creative arts-related digitized primary sources and other online materials are central to teaching and learning about history, civics, and/or democracy.</p> <p>&nbsp;</p> <p>Awards made under Lewis-Houghton Civics and Democracy Initiative must include rights-free materials from the Library’s music or creative arts digital collections, to develop curriculum, teaching materials, educational programs, pedagogical approaches, and/or other tools for history, civic and democracy instruction targeted toward middle and high school educators and learners.&nbsp;LHI awards should center on inquiry-driven analysis of primary sources, build learners’ civic skills and foster participation in our nation’s democracy.</p> <p>&nbsp;</p> <p>In addition to highlighting primary sources from the Library’s collections of music, dance, theater, visual arts, folk arts, film, photography, book arts, arts and literary manuscripts, and/or other creative arts, proposals may also include the use of arts-based pedagogies and other creative approaches. All proposals must expand the body of innovative strategies, tools, and materials for meaningful teaching and learning with Library of Congress materials.</p> <p>&nbsp;</p> <p>The focus of LHI awards includes the design of educational projects using Library of Congress materials for use in and outside of formal classroom settings. In addition to using Library primary sources to deliver history, civics, and/or democracy learning experiences integrating the arts, projects must address demonstrated educational needs of specific recipient populations and provide solutions that standard practice, documented experience, or research suggest would be effective. Organizations that receive LHI awards make up a subset of the TPS Educational Consortium whose work spans areas of interest including but not limited to arts integration, civics education, multimodal learning, and teaching with audiovisual primary sources.</p> <p><br></p> <p>Funded projects will support the Library’s mission to use its collections to connect with all Americans, including those representing multiple communities, beliefs and endeavors, to engage, inspire and inform Congress and the American people with a universal and enduring source of knowledge and creativity.</p> <p><br></p> <p>Projects must use the Library’s digital collections for one or more of the following approaches:</p> <p><br></p> <p>a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Deliver educational programming to various categories of educators and learners in secondary education (middle and high school);</p> <p>b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Create and distribute educational materials or tools for teaching specific content in history, civics, and/or democracy;</p> <p>c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Convene meetings of like organizations to devise strategies for furthering common learning and teaching goals with Library of Congress materials related to music and/or the arts; and/or</p> <p>d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Conduct research with significant practitioner involvement that investigates the impact of incorporating Library of Congress music and/or creative arts collections into history, civics, and/or democracy educational initiatives.</p> <p><br></p> <p><br></p> <p><strong>Questions and Answers</strong></p> <p><u>General Questions and Answers</u>: All questions relating to this Notice must be submitted via email to tps-grant@loc.gov no later than the date stated in Section B of the Notice (“General Questions Submission Deadline”). “The subject of each e-mail must read as follows: Notice 030ADV26R0050 – Lewis-Houghton Initiative New Awards – 2027.”</p> <p><br></p> <p>Answers will be provided in a Q&amp;A document uploaded to grants.gov. Questions received after the deadline(s) stated in Section B above may not be answered.</p> <p><br></p> <p><u>Technical Questions Submission:</u> Applicants experiencing problems with submitting proposals can request technical assistance until the date specified in Section B above (“Technical Questions Submission Deadline”).</p> <p><br></p>

030ADV26R0050

Award Ceiling

$100K

Closes

Sep 18, 2026

6d left

U.S. Mission to New ZealandClosing soon

Mission Australia APS, 2026

The U.S. Mission to Australia’s Public Diplomacy Section (PDS) announces an open competition to implement projects that advance U.S. economic, commercial, and security interests in Australia. This Annual Program Statement (APS) outlines strategic goals, expected outcomes, target audiences, eligibility criteria, and application guidelines for cooperative agreements ranging from $25,000 to $100,000, with a project duration of up to 24 months. Project proposals must address at least one of the following goals: • Promote flag football in Australia; • Combat antisemitism through Holocaust education; • Strengthen Pacific Islands partnership by highlighting shared cultural values among the peoples of the United States, Australia, and the Pacific Islands focusing on arts, cultural heritage preservation, education, and training. In addition to aligning with one of the strategic goals, applicants should clearly explain how they advance American leadership and excellence and how the projects deliver measurable results. All programs must include a clear connection to or inclusion of American expert(s), organization(s), or institution(s) or cultural elements in a specific field that will promote increased understanding of United States policy and perspectives. Please read the entire APS package before submitting an application. Applications must be submitted by September 20, 2026, for projects beginning as early as October 1, 2026. For more information, contact PASGrantsAustralia@state.gov. Applications that do not meet the eligibility criteria and do not contain all of the required information will not be considered.

OFOP0003732

Award Ceiling

$100K

Closes

Sep 20, 2026

8d left

Public & state institutions of higher education
National Institutes of HealthClosing soon

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 (P50 Clinical Trial Required)

Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPORE). The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this FOA, a group of highly related cancers are those that are derived from the same organ system, such as gastrointestinal, neuroendocrine, head and neck, and other cancers. Other programmatically appropriate groups of cancers may include those centered around a common biological mechanism critical for promoting tumorigenesis and/or cancer progression in organ sites that belong to different organ systems. For example, a SPORE may focus on cancers caused by the same infectious agent or cancers promoted and sustained by dysregulation of a common signaling pathway. In addition, a SPORE may focus on cross-cutting themes such as pediatric cancers or cancer health disparities. The research supported through this program must be translational and must stem from research on human biology using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must have the goal of reaching a translational human endpoint within the project period of the grant.

PAR-23-284

Award Ceiling

Closes

Sep 25, 2026

13d left

City or township governmentsNonprofits (non–higher education) with 501(c)(3)
National Institutes of Health

BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)

The purpose of this announcement is to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). Clinical studies supported may consist of acute or short-term procedures that are deemed Non-Significant Risk (NSR) by an Institutional Review Board (IRB), or Significant Risk (SR) studies that require an Investigational Device Exemption (IDE) from the FDA, such as chronic implants. The clinical trial should provide data to answer key questions about the function or final design of a device. This final device design may require most, if not all, of the non-clinical testing on the path to more advanced clinical trials and market approval. The clinical trial is expected to provide information that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. Activities supported by this Funding Opportunity include a small clinical trial to answer key questions about the function or final design of a device.As part of the BRAIN Initiative, NIH has initiated a Public-Private Partnership Program (BRAIN PPP) that includes agreements (Memoranda of Understanding, MOU) with a number of device manufacturers willing to make such devices available, including devices and capabilities not yet market approved but appropriate for clinical research. In general it is expected that the devices' existing safety and utility data will be sufficient to enable new IRB NSR or FDA IDE approval without need for significant additional non-clinical data. For more information on the BRAIN PPP, see http://braininitiative.nih.gov/BRAIN_PPP/index.htm

RFA-NS-25-022

Award Ceiling

Closes

Sep 28, 2026

16d left

Public And Indian Housing AuthoritiesNonprofits (non–higher education) without 501(c)(3)
DOC NOAA - ERA Production

FY 2024 – 2026 - Broad Agency Announcement (BAA) for the Office of Education

<p>This notice is not a mechanism to fund existing NOAA awards. The purpose of this notice is to request applications for special projects and programs associated with NOAA's strategic plan and mission goals, as well as to provide the general public with information and guidelines on how NOAA will select applications and administer discretionary Federal assistance under this Broad Agency Announcement (BAA). Each NOAA Line or Staff Office that supports financial assistance (National Marine Fisheries Service, National Ocean Service, National Weather Service, Office of Atmospheric Research, Office of Education, and National Environmental Satellite Data Information Service) has a separate BAA found in Grants.gov, so applicants should submit their application to the BAA for the Line Office that best fits their application. A description of NOAA Line Offices is found at https://www.corporateservices.noaa.gov/public/lineoffices.html and https://www.noaa.gov/office-education, and applicants may contact the Agency Contacts in Section VII. below for more information. If you submit the same application to more than Line Office, mention this in your application and notify the relevant contacts in Section VII. so that NOAA may coordinate internally. <span style="color: black;">&nbsp;</span></p>

NOAA-SEC-OED-2024-28060

Award Ceiling

$0

Closes

Sep 30, 2026

18d left

Department of Education

Institute of Education Sciences (IES): National Center for Education Research (NCER): Statistical and Research Methodology in Education, Assistance Listing Number (ALN) 84.305D

<p>The goal of the Statistical and Research Methodology in Education (Stats/Methods) grant program (84.305D) is to provide a wide range of methodological and statistical tools that will better enable applied education scientists to conduct rigorous education research.</p><p><br></p><p>Under this program, NCER will consider only applications that address one of the following topics: (1) Core Grants&nbsp;or (2) Toolkits, Guidelines, Compendia, Review Papers, and Curated Data Resources&nbsp;(Toolkits). The <strong>Core Grants topic </strong>supports the development of <em>new and improved</em> statistical and research methods for use by education researchers. These methods are to be user tested by education researchers to ensure their usability, revised as needed, then broadly disseminated through different types of products such as articles in applied education journals, detailed working papers and monographs, workshops, software, and curated data resources. The <strong>Toolkits Grants topic</strong> supports compiling <em>existing research and information</em> for a given method into products, such as toolkits, guidelines, compendia, review papers, curated data resources, workshops that help education researchers understand and apply the method. These products are to be user tested by education researchers to ensure their usability, revised as needed, and then broadly disseminated.</p><p><br></p><p>Assistance Listing Number (ALN) 84.305D.</p><p><br></p><p><br></p>

ED-GRANTS-080626-003

Award Ceiling

Closes

Oct 1, 2026

19d left

Department of Education

Institute of Education Sciences (IES): National Center for Education Research (NCER): Using Longitudinal Data to Support State Education Policymaking, Assistance Listing Number (ALN) 84.305S

<p><span style="color: rgb(0, 0, 0);">Through this grant program, IES supports state agencies’ use of their statewide longitudinal data systems (SLDSs) to provide evidence for their own program and policy decisions, and those of their local education agencies regarding increasing learners’ access to high-quality education and increased academic achievement.</span></p> <p><br></p> <p><span style="color: rgb(51, 51, 51);">Assistance Listing Number (ALN) 84.305S.</span></p>

ED-GRANTS-080626-004

Award Ceiling

$1.2M

Closes

Oct 1, 2026

19d left

Department of Education

Institute of Education Sciences (IES): National Center for Education Research (NCER): Research Training Programs in The Education Sciences, Assistance Listing Number (ALN) 84.305B

<p>NCER training programs prepare individuals to conduct education research that advances knowledge within the field and addresses issues important to education policymakers and practitioners.</p> <p><br></p> <p>Under this competition, NCER will consider only applications that address one of the following programs: (1) Early Career Development and Mentoring Program for Education Research (Early Career) or (2) Methods Training for Education Research (Methods Training). The <strong>Early Career</strong> program provides support for an integrated research and career development plan for early career investigators at institutions of higher education or non-academic research organizations who are developing education research careers. The <strong>Methods Training</strong> program funds training to help current education researchers, including state and local education agency research staff, maintain and enhance their research and analysis skills in order to conduct rigorous and relevant education research.&nbsp;</p> <p><br></p> <p><span style="color: rgb(51, 51, 51);">Assistance Listing Number (ALN) 84.305B.</span></p> <p><br></p>

ED-GRANTS-080626-001

Award Ceiling

Closes

Oct 1, 2026

19d left

Department of Education

Institute of Education Sciences (IES): National Center for Special Education Research (NCSER): Using Longitudinal Data to Support State Education Policymaking in Special Education, Assistance Listing Number (ALN) 84.324S

<p>Through this grant program, NCSER supports state agencies’ use of their statewide longitudinal data systems (SLDSs) to provide evidence for their own program and policy decisions, and those of their local education agencies pertaining to learners with or at risk for disabilities</p><p><br></p><p>Assistance Listing Number: 84.324S.</p>

ED-GRANTS-080626-005

Award Ceiling

$1.2M

Closes

Oct 1, 2026

19d left

Department of Education

Institute of Education Sciences (IES): National Center for Special Education Research (NCSER): Research Training Programs in Special Education, Assistance Listing Number (ALN) 84.324B

<p>NCSER training programs prepare individuals to conduct special education and early intervention research that advances knowledge within the field and addresses issues important to education policymakers and practitioners.</p> <p><br></p> <p>Under this competition, NCSER will consider only applications that address one of the following topics: (1) Early Career Development and Mentoring&nbsp;or (2) Methods Training for Special Education Research. The <strong>Early Career</strong> program provides support for an integrated research and career development plan for early career investigators at institutions of higher education or non-academic research organizations who have established an interest in special education research and are developing research careers focused on learners with or at risk for disabilities. The <strong>Methods Training</strong> program funds training to help current education researchers, including state and local education agency research staff, maintain and enhance their research and analysis skills in order to conduct rigorous and relevant research focused on learners with or at risk for disabilities. For FY 2027, NCSER is only accepting applications for Methods Training focused on analyzing large administrative datasets to address research questions related to learners with or at risk for disabilities.&nbsp;</p> <p><br></p> <p><span style="color: rgb(51, 51, 51);">Assistance Listing Number (ALN) 84.324B.</span></p>

ED-GRANTS-080626-002

Award Ceiling

Closes

Oct 1, 2026

19d left

National Institutes of Health

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications to support the validation of molecular/cellular/imaging markers (referred to as "markers" or "biomarkers") and assays for cancer detection, diagnosis, prognosis, monitoring, and prediction of response or resistance to treatment, as well as markers for cancer prevention and control. This FOA will support investigator-initiated research for both analytical, and clinical validation of assays to be used in cancer treatment, control, or prevention trials supported by the NCI. This NOFO will also support the validation of pharmacodynamic markers and markers of toxicity. Applicants should have assays that work on human samples and whose importance is well justified for development into clinical assays. As chemotherapies and/or radiation therapies are increasingly combined with immunotherapies to enhance the durability of anti-cancer responses, assays for measuring multiple markers, including immune markers, can be developed and validated simultaneously. The UH2 phase of this NOFO supports analytical validation of assays for these molecular/cellular/imaging markers, which must be achieved within 2 years before assays may undergo clinical validation. The UH3 phase of this NOFO supports clinical validation of analytically validated assays for up to 3 years using well-annotated biospecimens from retrospective or prospective clinical trials or studies. This NOFO may be used to validate existing assays for use in other cancer clinical trials, observational studies, or population studies. Efforts to harmonize clinical laboratory tests, including investigation into the performance and reproducibility of assays across multiple clinical laboratories, are also appropriate for this funding opportunity. Projects proposed for this NOFO will require multi-disciplinary collaboration among scientific investigators, oncologists, statisticians, and clinical laboratory scientist.

PAR-25-074

Award Ceiling

Closes

Oct 14, 2026

32d left

For-profit organizations (other than small businesses)Small businesses
National Institutes of Health

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to accelerate the adoption and validation of molecular/cellular/imaging markers (referred to as "markers" or "biomarkers") and assays for cancer detection, diagnosis, prognosis, monitoring, and prediction of response or resistance to treatment, as well as markers for cancer prevention and control. This NOFO will also support the validation of pharmacodynamic markers and markers of toxicity. Applicants to this NOFO must have an assay(s) whose performance has been analytically validated in specimens similar to those for the intended clinical use of the marker(s) and assay(s). As chemotherapies and/or radiation therapies are increasingly combined with immunotherapies to enhance the durability of anti-cancer responses, assays for measuring multiple markers, including immune markers, can be developed and validated simultaneously. The UH3 mechanism will support the clinical validation of established assays for up to 3 years using specimens from retrospective or prospective clinical trials or studies. This NOFO may be used to validate existing assays for use in other trials, observational studies, or population studies. Efforts to harmonize clinical laboratory tests, including investigation into the performance and reproducibility of assays across multiple clinical laboratories, are also appropriate for this funding opportunity. Projects proposed for this NOFO will require multi-disciplinary interaction and collaboration among scientific investigators, oncologists, statisticians, and clinical laboratory scientists. This NOFO is not intended to support early-stage development of technology or the conduct of clinical trials but is intended for validation of assays to the point where they could be integrated into clinical trials/studies as investigational assays.

PAR-25-075

Award Ceiling

$250K

Closes

Oct 14, 2026

32d left

OtherCity or township governments
Environmental Protection Agency

Innovative Water Infrastructure Workforce Development Grant

<p>The U.S. Environmental Protection Agency (EPA) is soliciting applications under the authority of the Safe Drinking Water Act (SDWA) section 1459E to accelerate career pipelines in the water utilities sector and provide access to water utility workforce opportunities. This action advances the Administration’s priorities, including the goals of Make America Healthy Again, by focusing on building the nation’s water workforce which is critical to ensuring public health and environment protection. Consistent with the law, this action will help inform people about the role of water and wastewater utilities in their communities and increase the awareness of water utility career opportunities.</p><p>The purpose of this funding opportunity is to support expanding career opportunities in the drinking water and wastewater utility sector and elevating public awareness about jobs in the water workforce. Eligible applicants under this funding opportunity are Institutions of Higher Education (IHEs), nonprofit organizations, and public works departments and agencies. Eligible activities include apprenticeship and internship programs, education programs designed for elementary, secondary, and higher education students, regional industry collaborations, and training programs designed to support decentralized workforce. Efforts should aim for measurable results and clearly show tangible benefits for water systems and communities. The proposed activities support the Agency’s Powering the Great American Comeback Initiative’s Pillar 1: Clean Air, Land, and Water for Every American. Examples include training individuals through an apprenticeship program and placing them into water sector jobs, training individuals for industry accreditation, and developing collaborations with community colleges, technical schools, utilities to address the water utility employment needs.</p>

EPA-OW-OWM-26-03

Award Ceiling

$7.8M

Closes

Oct 15, 2026

33d left

Department of Housing and Urban Development

Fair Housing Initiatives Program - Education and Outreach Initiative

Congress in 1988 established the Fair Housing Initiatives Program (FHIP) with a purpose of providing funding to entities to work alongside HUD to "prevent or eliminate discriminatory housing practices" 42 USC § 3616a(a). FHIP provides funds to eligible organizations through competitive grants. under several initiatives.The overarching purpose of the FHIP Education and Outreach Initiative (EOI) is to educate the public, housing providers and other stakeholders about their rights and obligations under provisions of fair housing laws, through the development, implementation, carrying out and coordinating or education and outreach programs. 42 USC § 3616a(d)(1); 24 CFR 125.301(a).The National Media Campaign component (EOI-NMC) is "designed to provide a centralized, coordinated effort for the development and dissemination of fair housing media products." 42 USC § 3616a(d)(1). A portion of NMC funds are specifically meant to increase participation in the annual national fair housing month. Under a cooperative agreement, HUD will exercise the right to approve, and have substantial involvement in, all proposed deliverables, as well as the Work Plan or Statement of Work (SOW).The General Component (EOI-GC) is designed to carry out projects programs that prevent or eliminate discriminatory housing practices by establishing or supporting regional, local, and community- based education and outreach activities, events, and programs. For grants and cooperative agreements, HUD will conduct monitoring reviews, request quarterly reports, and approve all proposed deliverables as documented in the applicant's Work Plan or SOW. Most EOI funds are awarded under grant agreements. However, national funds are awarded under cooperative agreements managed by Headquarters since the awards have a nationwide impact and therefore require more complex and frequent oversight as well as Departmental approval of deliverables.

OFH-2600-DC-021A

Award Ceiling

$2.5M

Closes

Nov 2, 2026

51d left

National Institutes of Health

Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

PAR-25-255

Award Ceiling

Closes

Nov 5, 2026

54d left

Nonprofits (non–higher education) without 501(c)(3)Federally recognized Native American tribal governments
National Institutes of Health

Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)

<p>Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.</p>

PAR-25-095

Award Ceiling

$350K

Closes

Nov 6, 2026

55d left

State governmentsCity or township governments
Office of Elementary and Secondary Education

Impact Aid Discretionary Construction Grant Program - 84.041C

The Employment and Training Administration at the U.S. Department of Labor (DOL) is soliciting applications in support of the administration of the Impact Aid Discretionary Construction Grant Program on behalf of the U.S. Department of Education (ED). The Impact Aid Discretionary Construction Grant Program provides grants to eligible Impact Aid Local Educational Agencies (LEAs) to assist in addressing their school facility emergency and modernization needs. This competition is limited to emergency grants that meet the absolute priority and other requirements in this notice. The competition uses existing statutory authority and appropriated funds to address urgent school facility needs in federally connected communities while promoting responsible stewardship of taxpayer dollars.

DOL-OESE-34832

Award Ceiling

$8.0M

Closes

Nov 10, 2026

59d left

Independent school districts
National Institutes of Health

Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

<p>Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.</p>

PAR-25-096

Award Ceiling

$200K

Closes

Nov 17, 2026

66d left

Public & state institutions of higher educationCounty governments
National Institutes of Health

National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of DCTD and OHAM. The proposed project must involve at least 1 clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and Alternative Medicine Program and/or the HIV and AIDS Malignancies Research Programs. Applicants may propose to conduct an early phase trial by itself, or in combination with another research aim(s) as appropriate.

PAR-25-081

Award Ceiling

$500K

Closes

Jan 7, 2027

117d left

For-profit organizations (other than small businesses)Other Native American Tribal Organizations
National Institutes of Health

Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, treatment, and/or disease status for cancer or other disease.

PAR-25-079

Award Ceiling

$500K

Closes

Jan 7, 2027

117d left

Special district governmentsFederally recognized Native American tribal governments
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